You have some swelling and bruising between your legs where the needles were put in. Your nurse will give you painkillers. Warm baths can also help.
You might need to have an enema to empty your bowel so that it is clear during the treatment. An enema is a liquid that you put into your back passage. Or you might have a liquid medicine (laxative). You need to stay close to a toilet for a few hours afterwards.
You might also have a heart tracing (ECG).
Pain and swelling
Permanent seed brachytherapy is a treatment for early stage prostate cancer. This means the cancer hasn’t spread outside of the prostate.
You might start taking a medicine called tamsulosin. It helps you to pass urine. And your doctor might give you antibiotics. They will tell you how long you need to take these medicines for.
It’s safe to have sex and sleep in the same bed as your partner after treatment. For a few months, when having sex you should wear a condom. This is in case a seed comes out.
You meet members of your treatment team. You sign the consent form to agree to the treatment and can ask questions. It helps to write down all your questions beforehand to take with you. The more you know about what is going to happen, the more confident you will feel.
Grapes are one of the most consumed fruits in the world and are rich in polyphenols. Grape seed proanthocyanidins (GSP) have demonstrated chemopreventive and/or chemotherapeutic effects in various cancer cell cultures and animal models. The clinical efficacy of chemotherapy is often limited by its adverse effects. Several studies show that reactive oxygen species mediate the cardiotoxicity and neurotoxicity induced by various cancer chemotherapeutic agents. This implies that concomitant administration of antioxidants may prevent these adverse effects. The review was carried out in accordance with the PRISMA guidelines. An electronic search strategy in Medline and Embase databases was conducted. Of the 41 studies reviewed, 27 studied GSP while the remainder (14) studied grape seed or skin extracts (GSE). All the studies were published in English, except 2 in Chinese. A significant percentage (34%) of the studies we reviewed assessed the effect of GSE or GSP on cardiotoxicity induced by chemotherapy. Doxorubicin was the most common chemotherapeutic drug studied followed by cisplatin. Research studies that assessed the effect of GSE or GSP on radiation treatment accounted for 22% of the articles reviewed. GSE/GSP ameliorates some of the cytotoxic effects on normal cells/tissues induced by chemo/radiotherapy.
The side effects of chemo depend on the type and dose of drugs given and how long they are taken. When chemo and radiation are given at the same time, side effects tend to be worse. Common side effects of chemo include:
For some people, the side effects of getting more than one chemo drug might be too much to handle. For those people, treatment with a single drug, such as gemcitabine or cisplatin, may be an option. Other drugs sometimes used alone for bladder cancer include, docetaxel, paclitaxel, doxorubicin, methotrexate, ifosfamide, and pemetrexed.
Chemotherapy (chemo) is the use of drugs to treat cancer. Chemo for bladder cancer can be given in 2 different ways:
Most bladder cancers are transitional cell (urothelial) cancers, but there are other types as well, including squamous cell carcinoma, adenocarcinoma, and small cell carcinoma. These rare types of bladder cancer may be treated with drugs different from those listed above.
Which chemo drugs are used to treat bladder cancer?
When chemo is given with radiation, the most common drugs used include:
Some chemo drugs can cause other, less common side effects. For example, drugs like cisplatin, docetaxel, and paclitaxel can damage nerves. This can sometimes lead to symptoms (mainly in the hands and feet) such as pain, burning or tingling, sensitivity to cold or heat, or weakness. This is called peripheral neuropathy.
When chemo drugs are given in pill form or injected into a vein (IV) or muscle (IM), the drugs go into the bloodstream and travel throughout the body. This is called systemic chemotherapy. Systemic chemo can affect cancer cells anywhere in the body.
Systemic chemo can be used :
For this treatment, the chemo drug is put right into the bladder. This type of chemo is used for bladder cancer that’s only in the lining of the bladder. It’s described in Intravesical Therapy for Bladder Cancer.