t could be just the Quitnet team, but it’s easy to get caught up in the medical benefits of CBD oils, their purity contents and effectiveness. We know these Koi cbd review. Koi cbd oil 350 mg. Koi cbd oil reviews. Koi cbd terpenes. Koi hemp oil. Koi prices. Cbd hemp oil drops. Koi high cbd levels in oil.
Koi CBD Review: Should You Buy? The Pros & Cons (2022)
t could be just the Quitnet team, but it’s easy to get caught up in the medical benefits of CBD oils, their purity contents and effectiveness. We know these things are extremely important, but where’s the balance in the products? We are still human and like to have fun right? Then Koi CBD enters the picture and tries to give us something new, fresh and exciting. Do they succeed? This is our Koi CBD review (updated for 2022).
2022 update: we no longer recommend Koi CBD.
Koi CBD’s customer support has really disappointed us. Members of our team (and other customers we spoke to) have complained about waiting weeks for a response. We hope Koi CBD improves on this soon.
If you’re looking for the best CBD oil, we suggest buying from cbdMD – our #1 pick for 2022. Click here to read our cbdMD review.
Koi CBD Review
Koi CBD believe in CBD oils improving your life just as much as the next company. Actually much more than the next CBD oil company, which is why this review is happening in the first place. They also believe that it’s okay to make their oils taste good!
Can a tasty CBD oil exist in the real world? That’s like some theoretical nonsense right?
Not entirely. Koi CBD has done their best to create some great flavors (such as blue raspberry) for those who don’t like vaping but want the cool flavors typically associated with CBD vape oils.
If you’ve been looking for a company that cares about your pain, creates a full spectrum oil and has a bit of fun in the process, Koi could be for you. They have a flair that is kind of contagious and genuinely are trying to change the world, one flavored oil at a time.
Sensitive (and picky) taste buds rejoice!
The Koi CBD Lineup
If you’ve googled ‘best CBD oils’ you are sure to have seen Koi CBD oil on almost every list (including ours). This is because they have made a name for themselves as a brand that strives for full transparency, corrects its mistakes and has proven its CBD oil is one of the best on the market time and time again.
Koi CBD Vape Juice is their most popular product. It’s a multifunctional oil that was created to be vaped but can also be taken orally, under the tongue, in the traditional manner.
Besides vape oils, Koi CBD also sells gummies, sprays, body lotion and a recently added Koi Naturals product in their lineup.
Koi Naturals is an all-natural, bare essentials CBD oil tincture. It is the most recent product line released by Koi.
Before Naturals, Koi CBD did not have a purely sublingual oil, your only option was taking the Vape Juice orally. You can understand why Quitnet was thrilled when Koi Naturals CBD was introduced.
The Koi Naturals product is designed to be taken orally or added to food and drinks and is available in two sizes: 30ml and 60ml.
- The 30ml size is available in 250mg, 500mg and 1000mg and comes in Spearmint, Lemon Lime, Orange and Natural flavors. Depending on the strength, the 30ml option ranges between $40 and $100.
They also come with dropper bottle tops for easy use. Hold the oil under your tongue for 15 – 30 seconds and then swallow. Do this 1-3 times a day for best results.
- The 60ml is their extra strength option. Choose between 1,500mg and 3,000mg and Spearmint or Natural flavor. This option ranges from $150 – $250.
Instead of a dropper, this one has a spray top. Spray under the tongue (for fastest absorption) 1-3 times a day.
This line is made up of 100% natural Koi CBD Full Spectrum oil and coconut oil. The full spectrum includes CBD, CBN, CBDV, and CBG, which all work together in synergy to provide ultimate benefits.
Is it really as good as they say it is? Are you serious? It’s great. But is it great for you?
You know by now the research that needs to be done on any CBD oil company before handing over your money. This poorly regulated industry is open to any and all, and it never ceases to amaze us at Quitnet just how awful some companies can be.
Rest assured Koi CBD is not one of those companies and Koi Naturals is not one of those products.
Why Choose Koi CBD?
There are certain standards that let you know right away if a CBD brand is worth giving a second look to:
- No THC
- Hexane and solvent free
- Pesticide free
If there’s one thing you can be sure of, Koi CBD takes pride in their new line. Their CBD purity sits at over 99% and they use the purest ingredients in order to produce the highest quality possible.
The hemp they use comes from Colorado, one of the best places in the world for hemp to prosper, and is packed with terpenes and cannabinoids.
Batches are tested for safety, purity, and consistency, and have been effective when used for stress, chronic pain, loss of appetite and foggy memory. The lab results have always come back very clean.
CBD Oil Quality
Koi CBD oil is absolutely clear so you know it is of the highest quality. Since coconut oil is colorless, it has no effect on the color of the oil whatsoever. A CBD oil that’s clear has had every impurity removed until all that is left is CBD.
For what you’re paying, Koi CBD seems to know how to make sure you feel like you’re getting your money’s worth. The bottle comes in a tall, slender gorgeous little box that makes you giddy upon seeing it. Inside the box sits the dark glass bottle containing the CBD oil.
A dark bottle is always appreciated by us here at Quitnet as it extends the shelf life of the oil and fights against the days you forget to store it properly.
The 60ml comes with a spray cap but also includes a dropper if you want to administer your dosages the more common way. Many people have unexpectedly fallen in love with the spray bottle top, however, because it gives them more control over their dosages.
The spray top is unique and adds a bit of fun to using the oil. It also makes it easier to add CBD to your food.
100% Natural Ingredients
If natural ingredients are important to your lifestyle, you’ll love this product. When Koi CBD says 100% natural they mean it. There are only 3 ingredients listed on the bottle: CBD, coconut oil and natural flavor extracts. This is CBD oil at the bare minimum and we love it.
You don’t have to sacrifice your natural lifestyle for flavor. Each of the flavors is natural but you can always get the “Natural” flavor they offer anyway.
One of the things we love about Koi CBD the most is they care about what their products taste like!
Because the Quitnet team is not full of bad people, we won’t name drop, but we will say this: there are some ridiculously disgusting tasting CBD oils on the market. Flavor isn’t (and shouldn’t be) the most important thing in the world, especially when it comes to a product that has so many benefits, BUT can things that are good for you also taste good? Is that asking for so much?
Koi Naturals doesn’t think so. In fact, they have been obviously putting their taste creators to work. If their Vape Juice lines tell you anything, they believe that healthy things can be yummy. Pure innovators.
Sorry about the rant, back to the review.
Spearmint seems to be the favorite but each flavor has found its way into the hearts of many. You can taste the hemp of the oil, but overall, for a naturally infused flavor, the taste is surprisingly good. Even the Natural flavor tastes better than most other CBD oils because of the coconut oil, giving the CBD oil a slightly sweet taste on your tongue.
Another great thing about the oils is that they do not noticeably change the flavor of your foods or drinks. You don’t have to worry about gagging or not being able to enjoy the benefits this oil has to offer.
A True Full Spectrum CBD
Koi Naturals is the brand’s first full spectrum offering. As a general rule, there is no true way of regulating the claim of a product being “full spectrum”. Most of the lab reports you’ll find are mostly composed of CBD with slight amounts of other cannabinoids. Often times there is no report even available about the amounts of terpene in a batch.
However, this isn’t the case with Koi CBD. The full spectrum they’ve touted in their Naturals line is no joke, and the lab reports prove it. We haven’t seen such a high-quality full spectrum CBD oil since Blessed CBD in the UK. The range of terpenes and cannabinoids present in their oil is wide. For those of you looking to experience the Entourage Effect (1), this product provides you the best chance.
Why is coconut oil so special you ask? Glad you asked!
One of the few talked about facts about CBD oils is that your body is not able to absorb the oil without help. In order for the CBD oil to absorb into your body, it needs a carrier oil and coconut oil is one of the best. It is digested quickly and is a great source of lauric acid, which contains antiviral and antibacterial properties.
This CBD-coconut oil blend absorbs into your body quickly and pulls no punches with its positive effects on your body.
ISO Lab Certification Status
More and more companies are offering third-party lab testing on their products, but Koi has managed to go above and beyond in this area as well.
Not only will you find their lab results, but you will see testing for the most recent batches of each specific product. To show their commitment to delivering the best product, they display all lab reports on the lab’s site. That’s right, they host their customer portal on the lab testing site! This lets you know they have no way to forge results or pick and choose what information to share.
Koi CBD leaves the customer with no doubt that it truly has a pure, effective, high-quality product to offer.
Value For Money
Koi Naturals may be a little expensive for some, but the bottle lasts much longer than you think and longer than the listed time Koi CBD provides. Many people report holding on to their bottles for longer than they believed they would due to the strength of the oil, making it cheaper over time.
For those who do not suffer from chronic pain, this bottle is a great value for the price.
Koi’s mission is to restore balance to everyone’s life through the magic of CBD and its beneficial properties. This includes veterans who they go above and beyond to help.
Due to the restrictive policies of the Veterans Administration, CBD oil cannot be prescribed by healthcare providers in the VA network. This means veterans who want to use CBD oils as health supplements may need help financially to access them.
Koi CBD offers veterans a lifetime 25% discount to help them purchase their products. Their discount is a bit higher than most, and indicates to veterans (and all their customers) that they care more about people than profits (but they do still care about profits).
Dedication To The CBD Industry
Making its debut to the CBD oil industry in 2015, Koi CBD is relatively young, but they are dedicated to their mission of 100% transparency.
Throughout the years they have added more and more analysis and lab reporting to their site for each product range. They encourage you to reach out to them for more information if you want to know anything more about a batch’s lab results or the process they use to manufacture oil.
Product & Effectiveness
Koi is a brand with personality and that alone gives them brownie points. It’s hard not to appreciate their dedication to creating tasty CBD products, and impossible not to smile while reading the flavors for some of their product (Tropical Popsicle and the Fuji Apple Nectarine Strawberry anyone?).
Though the Koi Naturals line doesn’t have the most creative names, Koi still provided its customers with variety, and who doesn’t like option?
A company that is innovative and doesn’t take itself too seriously tells Quitnet real human beings may work there.
And most importantly – this oil works. People have used it for pain, depression, insomnia, anxiety and chronic migraines to name a few. The coconut oil allows it to start working quickly and the purity gives maximum benefit. Many people have found (with the support of their healthcare providers) that they were able to gradually reduce their prescribed medications or treatments and use CBD oil instead.
It’s wonderful to have alternatives to manage daily health issues and this alternative is all-natural.
Koi Naturals has a lot going for it, it’s hard to really find issues that would keep us from recommending it but there are a few things that bothered us a little bit. Other Koi CBD oil reviews online also said the same thing.
What Could Be Better?
Customer service is always one of those things that you never know if it’s true until you need it. We regret to say this, but sadly, the customer support from Koi CBD was extremely disappointing. Members of our team had recently sent multiple questions to Koi CBD, but no response was ever received. Despite sending countless follow-up emails, we never heard back.
We’ve also received complaints from our readers about Koi CBD’s poor customer support, and it’s a shame because they are a brand that seems to be doing everything else right.
Not Quite 0% THC
They list the amount of THC found in their Koi Naturals as 0%, but if you take a look at their lab reports you’ll see there are traces of THC. While there are probably no detectable levels of THC and it will in no way have an effect on your concentration or get you high, it is good to read the reports, be careful and know the truth.
It is also quite common for full-spectrum oils to contain very tiny amounts of THC and should be of no concern.
We have to admit being a little disappointed at the lack of transparency on the process Koi uses to extract CBD from hemp. The best extraction process is CO2 extraction but it is not clearly stated what process they use. Some say Koi uses CO2 extraction since there is no solvent or pesticides in their lab reports, but Quitnet couldn’t verify this.
Clearly, the process is good enough to create a high-quality product, but if you are aiming at the title of most trusted brand, the extraction method used should be listed somewhere in plain sight.
Price & Money Back Guarantee
While certainly not the most expensive CBD oil on the market, it definitely isn’t the cheapest. The smaller bottles are priced above average; the larger size falls into the middle range when compared to other similar offerings from other brands.
They offer a variety pack for those interested in trying the flavors and there is a nice value when you get that. The quality of their products and small batch processing may justify the higher prices.
Of course, a money back guarantee isn’t a deal breaker, but we dislike this policy nonetheless. The journey to finding the right CBD oil can be expensive, time-consuming and discouraging for many people as they sift through the many brands available.
The fact that they have great pride in their product does encourage one to purchase, but not having a guarantee will make anyone see it as a risk and wonder why there is no money back guarantee if the product is as exceptional as the company claims.
Koi CBD entered the industry with a splash and has been enjoying, and solidifying, its place as one of the most trusted brands right now. They are innovative and dedicated to improving their offerings – which is all evident when you read the hundreds of Koi CBD reviews online.
There have undetectable levels of THC in their oil, a wide spectrum of terpenes and cannabinoids in their Koi Naturals offering, 100% natural ingredients, and all-natural flavors.
The Koi Naturals line is colorless, proof of its quality, and works quickly and effectively. The bottles last longer than the given time period, and with stronger strengths available, you can use this line for chronic pain, anxiety, insomnia, and concentration/focus.
However, their customer support is very poor and frustrating – and for this reason alone, we suggest buying your CBD oil elsewhere (such as from cbdMD).
Koi CBD Review
Our Rating: A. Innovate products and flavors with verified levels of CBD.
Koi CBD oil is a high-quality oil with guaranteed therapeutic concentrations of CBD. Their lab analyses check out in our research. Even though they include products like vape and gummies, their products actually contain therapeutic levels of CBD, a rarity in the industry. With cookie-cutter CBD companies, all franchises of one old hemp manufacturer, only the 25% oil and the concentrates actually have therapeutic levels of CBD. Not so with Koi. You can get enough CBD from grape vape or strawberry gummies with Koi. You don’t have to choose between fun or getting the CBD you need for stress and anxiety associated with various medical conditions. These products also contain the ‘entourage’ cannabinoids and terpenes like CBDV, CBG, limonene, and myrcene. We will focus on Koi Full Spectrum CBD oil but also go over information about the other products.
CBD oil can be used under the tongue or added to foods. It may be dissolved in hemp oil or coconut oil. This adds healthy fatty acids and MCTs to the mix. Koi produces CBD tinctures, vapes, topicals, supplements, gummies, and even pet products. Koi provides CBD in various flavors. None of these products will make you high. They are meant as dietary supplements.
Koi sources its hemp from the San Luis Valley between Colorado and New Mexico. This is an arid, sunny region between the valley and the headwaters of the river called the Rio Grande. In this environment, hemp grows resilient, lush, and packed with cannabinoids and terpenes.
Koi hemp oil
|Is its CBD oil?||Yes. It is both CBD oil and hemp oil.|
|Old, the trusted company?||No. Operating since 2015.|
|Contains verified therapeutic levels of CBD?||Yes.|
|Sourced in the United States?||Yes.|
|Sourced in Europe?||No.|
|Certified Organic in the US?||Unknown.|
|Certified Organic by the European Commission?||Unknown.|
|Did the lab test in the United States?||Yes.|
|3 rd Party Testing?||Yes.|
|Do they tell what percentage CBD in a product?||Yes.|
|CO2 extracted?||No. Solvent-free extraction.|
|Functional Website?||Yes. High function.|
From our grading questions above and our research, Koi CBD products get an A. If you have any suspicions about their products, send a sample of the product to a 3 rd party lab and leave a comment telling us your results.
Advantages of Koi Hemp Oil
The advantage of Koi Hemp products is that they provide guaranteed therapeutic levels of CBD in innovative and delicious products. With most companies, you can either have therapeutic levels of CBD, or you can have cool products with cheap hemp oil in them and little CBD.
Koi Vape products actually deliver a therapeutic level of CBD via vape. Most vape products will not deliver you a therapeutic dose even if you vape all day long. Koi has done the math and has the lab analyses to prove it. Even their Tropical Gummies has 10 mg of CBD per gummy! That is unheard of for CBD gummy candies, most of which just have hemp seed oil in them. The hemp seed oil has less than 25 parts per million of CBD.
One potential disadvantage of Koi is that they use a solvent-free extraction process for their CBD. We simply don’t know what this method is or if it produces a product of the caliber of supercritical CO2 extraction, or if it is worse or better. CO2 is the same stuff you breathe out, we know it’s fairly safe to use. Whatever method they use, we don’t know if it is more or less safe than CO2 extraction.
Koi CBD uses the Confident Cannabis lab result reporting system to report lab results for each batch of the product tested by the CannaSafe Labs. Get it? Confident Cannabis handles the lab reporting, CannaSafe laboratories do the testing. We will assume this is a third-party lab. And the lab results are very good, even for the vape products.
Koi prices and products
|CBD Oil||CBD Vape Juice||Devices and Cartridges||CBD for Pets||CBD Gummies||CBD Lotion||KOI CBD Hats|
|Koi Naturals Full-Spectrum CBD, Orange $39.99 – $99.99||CBD Vape Juice,
Pumpkin Spice Latte
$39.99 – $99.99
|Koi Stik by Boulder©
|Koi Naturals Soft Chews
|Koi CBD Tropical Gummies
$9.99 – $29.99
|Koi CBD Orange Hat
|Koi Naturals Full-Spectrum CBD, Lemon Lime
$39.99 – $99.99
|CBD Vape Juice, Blue Koi
$29.99 – $99.99
|Max Battery 380mAH
|Full Spectrum CBD Oil Spray
|Koi Naturals Full-Spectrum CBD, Spearmint
$39.99 – $99.99
|CBD Vape Juice, red koi
$29.99 – $99.99
|Koi Ponds (2 empty pods)
|CBD Combo Pack for Dogs
|Koi CBD Blue Hat
|Koi Naturals Full-Spectrum CBD, Natural
$39.99 – $99.99
|CBD Vape Juice, gold koi
$29.99 – $99.99
|Fitt Pods (2 pre-filled pods)
|Koi Naturals Infused with Koi PRIZM© Proprietary Full Spectrum Blend
$39.99 – $99.99
|CBD Vape Juice, white koi
$29.99 – $99.99
|Koi Naturals Vape Cartridge
|CBD Vape Juice, jade koi
$29.99 – $99.99
|CBD Vape Juice, pink koi
$29.99 – $99.99
Koi Naturals Full-Spectrum CBD Oil
8.5 mg to 34 mg of CBD per dropper.
5 mg to 2 mg of CBD per drop.
INGREDIENTS: coconut oil, Koi PRIZM™ full-spectrum CBD oil, natural orange flavor extract.
Directions: Consume a complete dropper (1mL or 30 drops), from one to three times daily. Hold under the tongue for 15–20 seconds, then swallow. Wait three hours after initial (first time) use to see how the strength level of CBD may affect you.
Koi CBD Vape Juice
Ingredients: 100% natural cannabidiol (CBD) isolate, food-grade vegetable glycerin, propylene glycol, natural & artificial flavorings
Made with 100% natural CBD, with full traceability from the start of extraction
A 3mL vape tank will hold 102 mg of CBD. This is one of the few vape products which clearly shows that you can get therapeutic levels of CBD through vaping. However, it has not been proven that vaping is an effective way to take the CBD.
Ingredients: organic aloe leaf juice, organic coconut oil, glycerin, emulsifying wax NF, stearic acid, organic jojoba seed oil, witch hazel water, organic alcohol extract, vitamin e oil, organic neem seed oil, rosemary leaf extract, Phenoxyethanol, rose distillate, lavender essential oil, organic white willow bark, xanthan gum, Tetrasodium EDTA, naturally occurring CBD in hemp oil.
What are the Main Ingredients for Koi Products?
The main ingredient is Koi CBD isolate or Koi PRIZM full-spectrum CBD blend which is created using a solvent-free method of extraction.
Products may also contain Koi CBD, terpenes, Koi Hemp oil, and/or CBD concentrates. CBD is cannabidiol, the main cannabinoid which produces most of the therapeutic effects by affecting cannabinoid receptors throughout the central nervous system. Terpenes provide fragrance, flavor, and boosts the effects of CBD. CBD Hemp oil drops are the combination of hemp seed oil with CBD isolate from CBD-Rich Whole Hemp Plant Extract.
How to Use
Koi has vape products that have therapeutic CBD levels. These are the first vape products we have seen to provide certificates of analysis showing that there are therapeutic CBD levels.
Koi specializes in flavorful edibles like gummies and flavored hemp oils which can be added to food or used under the tongue.
Koi’s CBD hemp oil drops can be used sublingually.
Koi Lavender is a lotion with therapeutic levels of CBD which can be applied as needed.
Koi CBD oil drops are an oil tincture that can be eaten with food or applied under the tongue.
Koi Naturals Full-Spectrum CBD Oil
One drop contains about 2 mg of CBD
For chronic pain, you might take 20 mg per day or 10 drops.
For non-medical anxiety in people who have epilepsy, up to 300 mg or 150 drops in divided doses throughout the day.
For the inability to sleep well at night, 20 drops, or 40 mg before bedtime daily.
For stress and tension in a person who has Huntington’s disease, 10 mg per kilogram of body weight, or 5 drops per kilogram of body weight.
For stress and tension in a person who has schizophrenia, up to 1,280 mg or 640 drops per day.
For glaucoma, absolutely no more than 40 mg or 20 drops per day. Higher doses can worsen symptoms.
Koi CBD Vape Juice
250mg CBD – 30mLBottleOne standard dropper holds about 10 mg of CBD from Koi Vape Juice. Therefore, a typical beginning dose for anxiety may be about 40 mg or four droppers in divided doses. For chronic pain, you might take 20 mg per day or 2 droppers. For non-medical anxiety in people who have epilepsy, up to 300 mg or 30 droppers in divided doses throughout the day. For the inability to sleep well at night, 4 droppers, or 40 mg before bedtime daily. For stress and tension in a person who has Huntington’s disease, 10 mg per kilogram of body weight, or one dropper per kilogram of body weight.For stress and tension in a person who has schizophrenia, up to 1,280 mg or 128 droppers per day.
For glaucoma, absolutely no more than 40 mg or 4 droppers per day. Higher doses can worsen symptoms.
Use a dime-sized amount to start, then gradually increase the dose until you get the desired effects. Use as much or as little as required.
Manufacturer, Support, Certificates
Norwalk, CA 90650
25% discount on all products to active duty and U.S. military veterans.
Pros and cons
- Has products like vape and gummies which have therapeutic levels of CBD
- Uses a unique lab reporting system so up-to-date labs are always available
- From seed to shelf, the process is transparent
- 3 rd party labs available
- Organic, non-GMO
- No pesticides
- No solvents
- Can be added to food
- Can be taken topically
- Can be used sublingually
- Contains CBD, small amounts of THC, and other cannabinoids
- Contains hemp oil with healthy fatty acids
- Balances the endocannabinoid system
- Contains MCT oil, a healthy fat
- Contains terpenoids
- Our research does not find a CBD concentrate product
- The solvent-free extraction method is unknown
Koi CBD Oil reviews
Review Rating: A. “It’s been wonderful.”
This reviewer in a Facebook group for Ehlers-Danlos syndrome said that Koi CBD oil has worked for her headaches, pain, and inflammation.
Review Rating: C. “Less effective…”
This Facebook reviewer switched to Koi CBD and found it less effective than his previous brand in helping to calm a 5-year-old with socially activated symptoms of ADHD.
Review Rating: A
This Facebook reviewer finds Koi CBD effective for anxiety.
Review Rating: A. “…the only one that worked…”
This Facebook reviewer found Koi vape juice to be the only vape that has worked; however, he feels that it is somewhat pricey.
Review Rating: A. “made me feel relaxed…”
This Reddit user finds Koi vape to be effective for fighting anxiety.
Q&A about Koi CBD
What amount can I vape?
Try using half of your favorite vape juice and half Koi CBD. However, you can also use Koi CBD vape as is.
Can I overdose on CBD?
There is no known overdose for CBD. As always, check the other ingredients in any product for which you may accidentally use more than recommended.
How long does it last? How to store it?
Avoid extremes of heat and cold. CBD can become crystal again from heat or cold. Your vape juice can last one year under proper conditions. Don’t leave it in a hot car or put it in the refrigerator.
Will it affect my work?
Koi CBD products contain no CBD and will not affect your working ability. It will reduce pain and anxiety which may improve working ability.
Will CBD interact with my meds?
You should consult your doctor to eliminate drug interactions. There have not been many reports of adverse drug interactions with CBD.
Is the big number on the bottle the mg amount per serving?
No. That is the amount of CBD in the entire bottle. To find the mg amount, you need to look on the website, under the product name, for ‘CBD concentration’. Products are formulated to provide a therapeutic dose.
Is sublingual better or vape?
Sublingual for now. It is not truly known if vape delivers therapeutic levels of CBD.
Is CBD the same as marijuana?
CBD stands for cannabidiol. It is a non-psychoactive cannabinoid, one among as many as 125 identified cannabinoids in industrial hemp.
CBD is not pot, marijuana, hash, weed, or cannabis sativa. Koi’s CBD products contain no psychoactive THC, only small amounts of therapeutic THC, with large amounts of therapeutic CBD. Marijuana usually contains THC which is psychoactive, CBD does not.
What other cannabinoids are found in hemp oil?
Hemp oil may contain over 125 cannabinoids, including:
- THC (tetrahydrocannabinol)
- THCV (tetrahydrocannabivarin)
- THCA (tetrahydrocannabinolic acid)
- CBV (cannabivarin)
- CBT (cannabicitran)
- CBN (cannabinol)
- CBDA (cannabidiolic acid)
- CBDV (cannabidivarin)
- CBE (cannabielsoin)
- CBG (cannabigerol)
- CBGM (cannabigerol monomethyl ether)
- CBGV (cannabigerovarin)
- CBL (cannabicyclol)
- CBD (cannabidiol)
- CBCV (cannabichromevarin)
- CBC (cannabichromene)
Is it legal?
Yes, with some caveats. CBD and CBDa are legal in most states of the United States as long as it comes along with no more than 0.3% THC. CBD all by itself is pretty much legal everywhere. However, you could still run into legal problems if you have a cop or court which is hell-bent on charging people with violation of marijuana laws or even laws about where you can buy non-psychoactive hemp. This is rare but has happened on occasion.
CBD is legal in many countries, including:
- Costa Rica,
- The Czech Republic,
- South Africa,
- Puerto Rico,
- Northern Ireland,
- Netherlands Antilles,
- Hong Kong,
- S. Virgin Islands,
How does CBD work?
CBD binds to receptors in the central nervous system including endocannabinoid receptors which help modulate the levels of monoamines, perceptions of pleasure and pain, and mood.
Does Koi provide 3 rd party labs on their website?
Yes, and the labs confirm that the CBD hemp oil product contains therapeutic levels of CBD.
What’s the difference between CBD, hemp oil, and hemp extract?
CBD means cannabidiol. It is a single cannabinoid, the second most abundant in marijuana and the most abundant in low THC hemp. Hemp oil is hemp seed oil. It contains healthy fatty acids, but only very low levels of CBD. Hemp extract is hemp oil extracted from the whole plant, standardized for levels of CBD. Unscrupulous companies will try to confuse consumers, passing off hemp seed oil as CBD. Koi CBD is legit and upright with its CBD levels.
Koi CBD oil and other Koi products seem to be very well made. They post lab results for each batch and list the CBD concentrations per bottle and per serving. This is unique among companies. Most companies leave you to do the math yourself so that you don’t find out you will have to vape 3 full bottles to get one sufficient dose of CBD. With Koi vape, a normal amount can get you a therapeutic amount of CBD. And they also have tasty flavors and great label designs. So, it seems they really did their homework, used their in house lab, then sent it to a 3 rd party lab.
CBD oil disclaimers (please read, this is important):
General Medical Disclaimer
Leaf Expert and its employees and partners do not represent the medical establishment and our information is not a replacement for your doctor’s advice.
Food and Drug Administration Disclaimer
The use of CBD products with the exception of Epidiolex and Sativex has not been evaluated or approved by the FDA. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Drug Screening Disclaimer
While most CBD products claim to have little to no THC, it is theoretically possible to fail a drug test for THC. This can happen because some CBD products have been tested to have far more THC than represented on the label. Also, CBD is similar in structure to THC.
About CBD and CBD-A
How it Works (scientific research)
Koi’s products have cannabidiol as the main active ingredient. Cannabidiol is known to have many mechanisms of action. We list the receptors in the central nervous system which cannabidiol binds to below. These include cannabinoid receptors, serotonin receptors, and orphan receptors which are related to cannabinoid receptors by their structure. CBD also modulates opioid receptors by which it affects pain perception. These are not the only receptors cannabidiol may bind to or effect.
Cannabidiolic acid (CBDa) have been shown to have the following effects:
- Fighting nausea (Rock, Limebeer, & Parker, Effect of combined doses of Δ 9 -tetrahydrocannabinol (THC) and cannabidiol acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley) models of conditioned gaping, 2015)
- Breast Cancer growth inhibitor (Takeda, et al., 2012)
- Anxiety fighter (Pertwee, et al., 2018)
- Vomiting fighter (Bolognini, et al., 2013)
- Depression fighter (Hen-Shoval, et al., 2018)
- Diarrhea fighter (Cluny, et al., 2011)
- Studied for inflammatory pain (Rock, Limebeer, & Parker, Effect of cannabidiolic acid and ∆9-tetrahydrocannabinol on carrageenan-induced hyperalgesia and edema in a rodent model of inflammatory pain., 2018)
Cannabidiol (CBD) has been shown to have the following health benefits:
- Anti-cancer (Massi, Solinas, Cinquina, & Parolaro, 2013).
- Anti-infarction (Hayakawa, et al., 2004).
- Anti-psychotic (Iseger, Bossong, & Bossong, 2015).
- Anti-seizure activity, known about in 1973 (Izquierdo, Orsingher, & Berardi, 1973).
- Attenuates the adverse effects of THC (Henquet & Kuepper, 2010).
- Can fight memory loss caused by marijuana THC(Morgan, Schafer, Freeman, & Curran, 2010). This means that medical marijuana should be enriched with extra cannabidiol to avoid memory loss and psychotic effects
- Fights cerebral infarction by modulating serotonin (Mishima, et al., 2005).
- Fights migration of cancer cells (Kapoor, 2013).
- Fights myocardial ischemia-reperfusion injury (Durst, et al., 2007).
- Inhibiting angiogenesis feeds cancers (Solinas, et al., 2012).
- May fight autoimmune diabetes (Weiss, et al., Cannabidiol arrests the onset of autoimmune diabetes in NOD mice, 2008)
- May fight colon cancer (Aviello, et al., 2012).
- May fight neurodegeneration (Iuvone, Esposito, Filippis, Scuderi, & Steardo, 2009).
- May help in colitis (Borrelli, et al., 2009).
- May reduce immune system inflammatory responses (Kozela, et al., 2010).
- Modulates sleep (Murillo-Rodríguez, Millán-Aldaco, Palomero-Rivero, Mechoulam, & Drucker-Colín, 2006).
- Neuroprotective (Hampson, Grimaldi, Axelrod, & Wink, 1998).
- Prevents diabetes (Weiss, et al., Cannabidiol lowers the incidence of diabetes in non-obese diabetic mice, 2006)
- Reduces anxiety in the right doses (Fusar-Poli, et al., 2009).
- Vasorelaxation (Stanley, Hind, Tufarelli, & O’Sullivan, 2015).
- Wakefulness-promoting, modulation of circadian rhythms (Murillo-Rodríguez, et al., 2014).
Cannabidiol and cannabidiolic acid work by binding to various receptor targets throughout the central nervous system and the rest of the body. Acting at these receptor sites, it exerts influence on the metabolism of various neurotransmitter systems. It seems like ‘snake oil’ that one compound can have all the beneficial effects listed above; however, cannabinoid receptors exist throughout the nervous system and it is known that such a ubiquitous receptor must be involved in nearly everything the nervous system does, just like serotonin and dopamine receptors. Dopamine affects pleasure, but also pain. Anxiety and also relaxation. Heart contraction and blood pressure. All of these systems are integrated so cannabinoid receptors will indeed have effects on all of these systems and exogenous cannabinoids from plants can definitely have therapeutic effects that are extensive.
Mechanisms of action of CBD
- CB1 receptor agonist
- CB2 receptor agonist
- Glitazone receptor agonist
- GPR12 (inverse agonist)
- GPR3 (inverse agonist)
- GPR55 (antagonist) receptors
- GPR6 (inverse agonist)
- Inhibitor of fatty acid amide hydrolase, increasing levels of endogenous cannabinoids
- Serotonin 5-HT1A receptor partial agonist
- An allosteric modulator of mu and sigma opioid receptors (Kathmann, Flau, Redmer, Tränkle, & Schlicker, 2006)
The action of CBD and CBDa produces anti-inflammatory, anti-pain, and anti-seizure effects which can help relieve stress in a range of discomforting conditions.
Does CBD have any side effects?
CBD is unlikely to have many side effects under 300 mg daily. Above that dosage, one should consult a doctor.
Before we look at the side effects, let’s look at the safety. Consider these facts:
CBD Safety facts
- Does not induce changes in food intake
- Does not induce catalepsy
- CBD is non-toxic
- Does not affect physiological parameters such as:
- Heart rate
- Blood pressure
- Body temperature
- Does not affect gastrointestinal movement
- Does not alter the psychomotor function
- It does not alter psychological functions.
- Chronic use and high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans.
(Bergamaschi, Queiroz, Zuardi, & Crippa, 2011)
Now, here are the side effects which have been reported:
Possible Negative Side Effects of CBD
- Inhibition of hepatic drug metabolism (possible drug interactions)
- Decreased fertilization capacity
- Decreased activities of p-glycoprotein and other drug transporters
- Alterations of in vitro cell viability
- Poor quality sleep
- Decreased appetite
- Changes in appetite
In general, CBD is safe and well-tolerated. Doses above 300 mg should have a doctor’s monitoring. Your doctor should manage drug interactions.